top of page
© 2021-2024 Marine Pharmacology

During the period 1998-2018, the global marine pharmaceutical preclinical pipeline involved research with more than 1,000 marine chemicals which demonstrated antibacterial, anticoagulant, anti-inflammatory, antifungal, anthelmintic, antiplatelet, antiprotozoal, and antiviral activities; actions on the cardiovascular, endocrine, immune, and nervous systems; and other miscellaneous mechanisms of action. The marine pharmaceutical preclinical pipeline is reviewed in the following 19 peer-reviewed articles:

20.

Mayer, A.M.S., V.A. Mayer, M. Swanson-Mungerson, M.L. Pierce, A.D. Rodriguez, F. Nakamura,  and O. Taglialatela-Scafati, Marine Pharmacology in 2019–2021: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action. Mar.Drugs 2024, 22(7), 309; https://doi.org/10.3390/md22070309

19.

Mayer, A.M.S., M.L. Pierce,  K. Howe, A.D. Rodriguez, Orazio Taglialatela-Scafati, F. Nakamura,  and N. Fusetani. Marine Pharmacology in 2018: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-inflammatory, Antiprotozoal, Antituberculosis, Antiviral and Anthelmintic Activities; affecting the Immune and Nervous System, and other Miscellaneous Mechanisms of Action. Pharmacological Research 2022 Aug 6;106391. Published on July 17, 2022 and available at  https://doi.org/10.1016/j.phrs.2022.106391

18.

Mayer, A.M.S., A.J. Guerrero,  A.D. Rodriguez, Orazio Taglialatela-Scafati, F. Nakamura,  and N. Fusetani. Marine Pharmacology in 2016-2017: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-inflammatory, Antiprotozoal, Antituberculosis, Antiviral and Anthelmintic Activities; affecting the Immune and Nervous System, and other Miscellaneous Mechanisms of Action. MARINE DRUGS 19 (2), 49, 2021. Published on January 21, 2021 and available at  https://www.mdpi.com/1660-3397/19/2/49

17.

Mayer, A.M.S., A.J. Guerrero,  A.D. Rodriguez, Orazio Taglialatela-Scafati, F. Nakamura,  and N. Fusetani. Marine Pharmacology in 2014-2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-inflammatory, Antiprotozoal, Antituberculosis, Antiviral and Anthelmintic Activities; affecting the Immune and Nervous System, and other Miscellaneous Mechanisms of Action. MARINE DRUGS 18, 5, 2019. Published on December 19, 2019 and available at  https://www.mdpi.com/1660-3397/18/1/5

16.

Mayer, A.M.S., A.D. Rodriguez, Orazio Taglialatela-Scafati and N. Fusetani. Marine pharmacology in 2012-2013: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; affecting the Immune and Nervous System, and other Miscellaneous Mechanisms of Action. MARINE DRUGS 15:273-334, 2017. Published on August 29, 2017 and available at  http://www.mdpi.com/1660-3397/15/9/273

15.

Mayer, A.M.S., A.D. Rodriguez, Orazio Taglialatela-Scafati and N. Fusetani. Marine pharmacology in 2009-11: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; affecting the Immune and Nervous System, and other Miscellaneous Mechanisms of Action. MARINE DRUGS 11:2510-2573, 2013. Published July 16, 2013 and available at  http://www.mdpi.com/1660-3397/11/7/2510

14.

Mayer, A.M.S., A.D. Rodriguez, R. Berlinck and N. Fusetani.  Marine pharmacology in  2007-8:  Marine Compounds with Antibacterial, Anticoagulant, Antifungal, Anti-inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; affecting the Immune and Nervous System, and other Miscellaneous Mechanisms of Action.  Comparative Biochemistry and Physiology Part C: 153: 191-222, 2011. Published on September 15, 2010 and available at https://pubmed.ncbi.nlm.nih.gov/20826228/  

PDF Doc

13.

K.B. Glaser and Mayer, A.M.S. A Renaissance in Marine Pharmacology: From Preclinical Curiosity to Clinical Reality.  Biochemical Pharmacology 78: 440-448, 2009. Published on April 22, 2009 and available at https://pubmed.ncbi.nlm.nih.gov/19393227/
PDF Doc

12.

Mayer, A.M.S., A.D. Rodriguez, R. Berlinck and M.T. Hamann.  Marine pharmacology in  2005-6:  Marine Compounds with Antibacterial, Anticoagulant, Antifungal, Anthelmitic, Anti-inflammatory, Antiprotozoal, and Antiviral Activities; affecting the Cardiovascular, Endocrine, Immune and Nervous Systems and other Miscellaneous Mechanisms of Action. Biochimica et Biophysica Acta, General Subjects, 1790: 283-308, 2009. Published March 19, 2009 and available at https://pubmed.ncbi.nlm.nih.gov/19303911/

PDF Doc

11.

Mayer, A.M.S. and K. R. Gustafson.  Marine Pharmacology in 2005-6: Antitumor and Cytotoxic Compounds. European Journal of Cancer 44:2357-2387, 2008. Published on August 11, 2008 and available at https://pubmed.ncbi.nlm.nih.gov/18701274/

PDF Doc

10.

Mayer, A.M.S., A.D. Rodriguez, R. Berlinck and M. T. Hamann. Marine pharmacology in 2003-4: Marine Compounds with Anthelminthic, Antibacterial, Anticoagulant, Antifungal, Anti-inflammatory, Antimalarial, Antiplatelet, Antiprotozoal, Antituberculosis, and Antiviral Activities;  affecting the Cardiovascular, Immune and Nervous Systems and other Miscellaneous Mechanisms of Action. Comparative Biochemistry and Physiology Part C:145: 553-581, 2007. Published on February 9, 2007 and available at https://pubmed.ncbi.nlm.nih.gov/17392033/

PDF Doc

9.

Mayer, A.M.S. and K. R. Gustafson, Marine Pharmacology in 2003-4: Antitumor and Cytotoxic Compounds. European Journal  of Cancer 43:2241-2270, 2006. Published on August 9, 2006 and available at https://pubmed.ncbi.nlm.nih.gov/16901686/

PDF Doc

8.

Mayer, A.M.S. and M. T. Hamann. Marine pharmacology in 2001-2: Marine Compounds with Antibacterial, Anticoagulant, Antifungal, Anti-inflammatory, Antimalarial, Antiplatelet, Antiprotozoal, Antituberculosis, and Antiviral Activities;  affecting the Cardiovascular, Immune and Nervous Systems and other Miscellaneous Mechanisms of Action. Comparative Biochemistry and Physiology Part C 140(3-4):265-286, 2005. 


PubMed Abstract      PDF Doc

7.

Mayer, A.M.S. and K. R. Gustafson, Marine Pharmacology in 2001-2: Antitumor and Cytotoxic Compounds. European Journal  of Cancer 40(18) 2676-2704, 2004. Published on September 5, 2004 and available at 

https://pubmed.ncbi.nlm.nih.gov/15571951/

PDF Doc

6.

Mayer, A.M.S. and M. T. Hamann. Marine pharmacology in 2000: Marine Compounds with Antibacterial, Anticoagulant, Antifungal, Anti-inflammatory, Antimalarial, Antiplatelet, Antiprotozoal, Antituberculosis, and Antiviral Activities;  affecting the Cardiovascular, Immune and Nervous Systems and other Miscellaneous Mechanisms of Action, Marine Biotechnology, 6: 37-52, 2004. Published on November 3, 2003 and available at https://pubmed.ncbi.nlm.nih.gov/14583811/

PDF Doc

5.

Mayer, A.M.S. and K. R. Gustafson, Marine Pharmacology in 2000: Antitumor and Cytotoxic Compounds. International Journal of Cancer 105: 291-299, 2003. Published on June 20, 2003 and available at https://pubmed.ncbi.nlm.nih.gov/12704660/

PDF Doc

4.

Mayer, A.M.S. and M. T. Hamann. Marine pharmacology in 1999: Marine Compounds with Antibacterial, Anticoagulant, Antifungal, Anthelmintic, Anti-inflammatory, Antiplatelet, Antiprotozoal, and Antiviral Activities; affecting the Cardiovascular, Endocrine, Immune and Nervous Systems and other Miscellaneous Mechanisms of Action,  Comparative Biochemistry and Physiology,  Part C 132/3: 315-339, 2002.


PubMed Abstract      PDF Doc

3.

Mayer, A.M.S. and V.K.B. Lehmann. Marine Pharmacology in 1999: Antitumor and Cytotoxic Compounds.  Anticancer Research  21: 2489-2500, 2001.

 
PubMed Abstract     PDF Doc

2.

Alejandro M. S. Mayer and Virginia K. B. Lehmann, Marine Pharmacology in 1998:  Marine Compounds with Antibacterial, Anticoagulant, Anti-inflammatory, Anthelmintic, Antiplatelet, Antiprotozoal, and Antiviral Activities; with actions on the Cardiovascular, Endocrine, Immune, and Nervous Systems; and other Miscellaneous Mechanisms of Action. The Pharmacologist 42(2):62-69, 2000.


PDF Doc 

1.

Alejandro M. S. Mayer, Marine Pharmacology in 1998: Antitumor and Cytotoxic Compounds. The Pharmacologist 41(4):159-164, 1999.


PDF Doc

© 2021-2024 Marine Pharmacology
bottom of page